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Unlike current therapies that target one or two pathways, retatrutide acts on: GLP-1 receptor GIP receptor Glucagon receptor This multi-target approach aims to improve weight loss while also enhancing metabolic health

This is important because recent research suggests that leptin resistance may be the main factor in why traditional calorie-restricted diets dont work.3 In this article, well outline the causes of leptin resistance and offer an eating plan that can help reverse it