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Activation of immune cells Some DAMPs function as chemoattractants, directly recruiting neutrophils [248]

High levels of each trigger inflammation and pain

According to data from the World Health Organization, approximately 225,000 new ovarian cancer cases are reported globally each year, with HGSOC accounting for the vast majority, and its mortality rate ranking among the highest of all gynecological malignancies ( HGSOC is typically diagnosed at an advanced stage, a phenomenon that results in an extremely poor prognosis, as the absence of early diagnosis and effective treatment contributes to a continuous increase in mortality rates (6)

A central question to be addressed is: How should land use and transport systems, from the city to the street level, be planned and developedconsidering both processes and projectsto ensure high levels of walkability and encourage more walking