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In addition, it was found that in 12-O-tetradecanoylphorbol-13-acetate (2.5 g/ear)-induced ear edema mouse models, L-theanine could downregulate the expression of platelet endothelial adhesion molecule-1 (PECAM-1) and decrease the production of pro-inflammatory factors, including IL-1, tumor necrosis factor-alpha (TNF-), and COX-2, which were significantly expressed in neutrophils, thus improving the infiltration and activation of neutrophils (30)

Gestating and lactating mares, young growing horses, and performance horses have the greatest need for vitamin E supplementation, especially those that do not have access to lush, green pasture

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