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There are three levels of classification of atypical melanocytic lesions: mild atypia in a melanocytic lesion moderate atypia in a melanocytic lesion severe atypia in a melanocytic lesion Most pathologists regard mild and moderate atypia synonymously

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Other Phase-I enzymes include keto-reductase, aldehyde dehydrogenase, carboxylesterases, and dihydropyrimidine dehydrogenase (DPD), which is one of the best-characterized functional variants affecting anticancer agents