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The Molecular Targets Driving the Revolution Modern incretin-based therapies harness three key hormone receptors that work together to regulate glucose metabolism, appetite, and energy balance: GLP-1R (Glucagon-Like Peptide-1 Receptor) Activated by drugs such as Semaglutide , this receptor stimulates insulin secretion, slows gastric emptying, and promotes satiety, helping reduce food intake and improve blood glucose control

Activates the same central pathways via nasal absorption, allowing for quicker systemic uptake